Eosinophils induce DC maturation, regulating immunity

Larvae by Regulating Local Immunity Eosinophils Preserve Parasitic Nematode

Eosinophils Mediate Protective Immunity

DC targeting DNA vaccines induce protective and therapeutic antitumor immunity in mice.

BACKGROUND Anti-CD11c antibodies target to the CD11c receptor that mediates antigen presentation to T cells by dendritic cells (DCs). To exploit these properties for immunization purposes, we obtained DC-targeting DNA vaccines by fusing tumor-associated antigen HER2/neu ectodomain to single chain antibody fragment (scFv) from N418 (scFv(N418)), a monoclonal antibody binding the mouse DC-restric...

Regulating protective immunity in atherosclerosis.

Atherosclerosis is a disease characterized by chronic inflammation. Looking back it is almost embarrassing how long it took for us to realize that the presence of these innate immune responses also was associated with activation of adaptive immunity. The first hints of an involvement of adaptive immunity in atherosclerosis came from studies performed by Göran Hansson and his coworkers about 20 ...

Nonpathogenic, environmental fungi induce activation and degranulation of human eosinophils.

Eosinophils and their products are probably important in the pathophysiology of allergic diseases, such as bronchial asthma, and in host immunity to certain organisms. An association between environmental fungal exposure and asthma has been long recognized clinically. Although products of microorganisms (e.g., lipopolysaccharides) directly activate certain inflammatory cells (e.g., macrophages)...